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Human Beta-synuclein (aa 1-134)

SNCB Swiss Prot#

Q16143

SNCB Protein names

Beta-synuclein

SNCB Gene names

SNCB

Organism

Human

SNCB Entry name

SYUB_HUMAN

SNCB Codon optimized cDNA(gene) Clone

SNCB Cat #

RPX0724

Tag

SNCB contains A 6x histidine tag

SNCB Formulation

Liquid

SNCB Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SNCB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SNCB Protein

SNCB Cat #

PX0724

SNCB Source

recombinant

SNCB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SNCB Purity

>90%, as determined by SDS-PAGE under reducing conditions

SNCB Activity

N/A

Tag

SNCB Contains A 6x histidine tag

SNCB Formulation

Liquid

SNCB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SNCB family

Synuclein family

SNCB Subcellular locations

Cytoplasm.

SNCB FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

SNCB Sequence

DDBJ

EMBL

GenBank

SNCB 3D structure

ModBase

SNCB interaction

STRING

SNCB Proteomic

PRIDE

SNCB Genome annotation

Ensembl

GeneID

KEGG

UCSC

SNCB Organism specific

CTD

MGI

SNCB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SNCB Gene expression

Bgee

ArrayExpress

Genevestigator

SNCB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY