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Human Drebrin-like protein (aa 1-430)

CMAP Swiss Prot#

Q9UJU6

CMAP Protein names

Drebrin-like protein (Drebrin-F) (SH3 domain-containing protein 7) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein)

CMAP Gene names

DBNL CMAP SH3P7 PP5423

Organism

Human

CMAP Entry name

DBNL_HUMAN

CMAP Codon optimized cDNA(gene) Clone

CMAP Cat #

RPX0719

Tag

CMAP contains A 6x histidine tag

CMAP Formulation

Liquid

CMAP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CMAP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CMAP Protein

CMAP Cat #

PX0719

CMAP Source

recombinant

CMAP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CMAP Purity

>90%, as determined by SDS-PAGE under reducing conditions

CMAP Activity

N/A

Tag

CMAP Contains A 6x histidine tag

CMAP Formulation

Liquid

CMAP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CMAP family

ABP1 family

CMAP Subcellular locations

Cytoplasm > cytoskeleton. Cell projection > lamellipodium.

CMAP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.

CMAP Sequence

DDBJ

EMBL

GenBank

CMAP 3D structure

ModBase

CMAP interaction

STRING

CMAP Proteomic

PRIDE

CMAP Genome annotation

Ensembl

GeneID

KEGG

UCSC

CMAP Organism specific

CTD

MGI

CMAP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CMAP Gene expression

Bgee

ArrayExpress

Genevestigator

CMAP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY