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Human Alpha-2B adrenergic receptor (aa 1-450)

ADRA2L1 Swiss Prot#

P18089

ADRA2L1 Protein names

Alpha-2B adrenergic receptor (Alpha-2B adrenoreceptor) (Alpha-2B adrenoceptor) (Alpha-2BAR) (Alpha-2 adrenergic receptor subtype C2)

ADRA2L1 Gene names

ADRA2B ADRA2L1 ADRA2RL1

Organism

Human

ADRA2L1 Entry name

ADA2B_HUMAN

ADRA2L1 Codon optimized cDNA(gene) Clone

ADRA2L1 Cat #

RPX0669

Tag

ADRA2L1 contains A 6x histidine tag

ADRA2L1 Formulation

Liquid

ADRA2L1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ADRA2L1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ADRA2L1 Protein

ADRA2L1 Cat #

PX0669

ADRA2L1 Source

recombinant

ADRA2L1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ADRA2L1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ADRA2L1 Activity

N/A

Tag

ADRA2L1 Contains A 6x histidine tag

ADRA2L1 Formulation

Liquid

ADRA2L1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ADRA2L1 family

G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2B sub-subfamily

ADRA2L1 Subcellular locations

Cell membrane; Multi-pass membrane protein.

ADRA2L1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

ADRA2L1 Sequence

DDBJ

EMBL

GenBank

ADRA2L1 3D structure

ModBase

ADRA2L1 interaction

STRING

ADRA2L1 Proteomic

PRIDE

ADRA2L1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ADRA2L1 Organism specific

CTD

MGI

ADRA2L1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ADRA2L1 Gene expression

Bgee

ArrayExpress

Genevestigator

ADRA2L1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY