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Human Endothelin-1 receptor (aa 21-427)

ETA Swiss Prot#

P25101

ETA Protein names

Endothelin-1 receptor (Endothelin A receptor) (hET-AR) (ETA-R) (ET-A)

ETA Gene names

EDNRA ETA ETRA

Organism

Human

ETA Entry name

EDNRA_HUMAN

ETA Codon optimized cDNA(gene) Clone

ETA Cat #

RPX0652

Tag

ETA contains A 6x histidine tag

ETA Formulation

Liquid

ETA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ETA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ETA Protein

ETA Cat #

PX0652

ETA Source

recombinant

ETA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ETA Purity

>90%, as determined by SDS-PAGE under reducing conditions

ETA Activity

N/A

Tag

ETA Contains A 6x histidine tag

ETA Formulation

Liquid

ETA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ETA family

G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamily

ETA Subcellular locations

Cell membrane; Multi-pass membrane protein.

ETA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

ETA Sequence

DDBJ

EMBL

GenBank

ETA 3D structure

ModBase

ETA interaction

STRING

ETA Proteomic

PRIDE

ETA Genome annotation

Ensembl

GeneID

KEGG

UCSC

ETA Organism specific

CTD

MGI

ETA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ETA Gene expression

Bgee

ArrayExpress

Genevestigator

ETA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY