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Human Substance-P receptor (aa 1-407)

NK1R Swiss Prot#

P25103

NK1R Protein names

Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)

NK1R Gene names

TACR1 NK1R TAC1R

Organism

Human

NK1R Entry name

NK1R_HUMAN

NK1R Codon optimized cDNA(gene) Clone

NK1R Cat #

RPX0627

Tag

NK1R contains A 6x histidine tag

NK1R Formulation

Liquid

NK1R Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NK1R Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NK1R Protein

NK1R Cat #

PX0627

NK1R Source

recombinant

NK1R Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NK1R Purity

>90%, as determined by SDS-PAGE under reducing conditions

NK1R Activity

N/A

Tag

NK1R Contains A 6x histidine tag

NK1R Formulation

Liquid

NK1R Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NK1R family

G-protein coupled receptor 1 family

NK1R Subcellular locations

Cell membrane; Multi-pass membrane protein.

NK1R FUNCTION According to UniProtKB Swiss Prot

FUNCTION: This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

NK1R Sequence

DDBJ

EMBL

GenBank

NK1R 3D structure

ModBase

NK1R interaction

STRING

NK1R Proteomic

PRIDE

NK1R Genome annotation

Ensembl

GeneID

KEGG

UCSC

NK1R Organism specific

CTD

MGI

NK1R Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NK1R Gene expression

Bgee

ArrayExpress

Genevestigator

NK1R Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY