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Human Sphingosine 1-phosphate receptor 5 (aa 1-398)

EDG8 Swiss Prot#

Q9H228

EDG8 Protein names

Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8) (Endothelial differentiation G-protein-coupled receptor 8)

EDG8 Gene names

S1PR5 EDG8

Organism

Human

EDG8 Entry name

S1PR5_HUMAN

EDG8 Codon optimized cDNA(gene) Clone

EDG8 Cat #

RPX0620

Tag

EDG8 contains A 6x histidine tag

EDG8 Formulation

Liquid

EDG8 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

EDG8 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant EDG8 Protein

EDG8 Cat #

PX0620

EDG8 Source

recombinant

EDG8 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

EDG8 Purity

>90%, as determined by SDS-PAGE under reducing conditions

EDG8 Activity

N/A

Tag

EDG8 Contains A 6x histidine tag

EDG8 Formulation

Liquid

EDG8 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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EDG8 family

G-protein coupled receptor 1 family

EDG8 Subcellular locations

Cell membrane; Multi-pass membrane protein.

EDG8 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

EDG8 Sequence

DDBJ

EMBL

GenBank

EDG8 3D structure

ModBase

EDG8 interaction

STRING

EDG8 Proteomic

PRIDE

EDG8 Genome annotation

Ensembl

GeneID

KEGG

UCSC

EDG8 Organism specific

CTD

MGI

EDG8 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

EDG8 Gene expression

Bgee

ArrayExpress

Genevestigator

EDG8 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY