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| Human G-protein coupled receptor 109B (aa 1-387) |
| HM74B Swiss Prot# | | P49019 |
| HM74B Protein names | | G-protein coupled receptor 109B (Niacin receptor 2) (Nicotinic acid receptor 2) (G-protein coupled receptor HM74B) (G-protein coupled receptor HM74) |
| HM74B Gene names | | GPR109B HM74B NIACR2 |
| Organism | | Human |
| HM74B Entry name | | G109B_HUMAN |
| HM74B Codon optimized cDNA(gene) Clone |
| HM74B Cat # | | RPX0601 |
| Tag | | HM74B contains A 6x histidine tag |
| HM74B Formulation | | Liquid |
| HM74B Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| HM74B Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant HM74B Protein |
| HM74B Cat # | | PX0601 |
| HM74B Source | | recombinant |
| HM74B Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| HM74B Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| HM74B Activity | | N/A |
| Tag | | HM74B Contains A 6x histidine tag |
| HM74B Formulation | | Liquid |
| HM74B Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant HM74B Products | | For pricing and availability Click Here >>> |
| HM74B family | | G-protein coupled receptor 1 family |
| HM74B Subcellular locations | | Cell membrane; Multi-pass membrane protein. |
| HM74B FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. |
| HM74B Sequence | | DDBJ | EMBL | GenBank |
| HM74B 3D structure | | ModBase |
| HM74B interaction | | STRING |
| HM74B Proteomic | | PRIDE |
| HM74B Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| HM74B Organism specific | | CTD | MGI |
| HM74B Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| HM74B Gene expression | | Bgee | ArrayExpress | Genevestigator |
| HM74B Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |