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Human G-protein coupled receptor 120 (aa 1-377)

GPR129 Swiss Prot#

Q5NUL3

GPR129 Protein names

G-protein coupled receptor 120 (G-protein coupled receptor PGR4) (G-protein coupled receptor GT01) (G-protein coupled receptor 129)

GPR129 Gene names

GPR120 GPR129 PGR4

Organism

Human

GPR129 Entry name

O3FA1_HUMAN

GPR129 Codon optimized cDNA(gene) Clone

GPR129 Cat #

RPX0582

Tag

GPR129 contains A 6x histidine tag

GPR129 Formulation

Liquid

GPR129 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

GPR129 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant GPR129 Protein

GPR129 Cat #

PX0582

GPR129 Source

recombinant

GPR129 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

GPR129 Purity

>90%, as determined by SDS-PAGE under reducing conditions

GPR129 Activity

N/A

Tag

GPR129 Contains A 6x histidine tag

GPR129 Formulation

Liquid

GPR129 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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GPR129 family

G-protein coupled receptor 1 family

GPR129 Subcellular locations

Cell membrane; Multi-pass membrane protein.

GPR129 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids (By similarity).

GPR129 Sequence

DDBJ

EMBL

GenBank

GPR129 3D structure

ModBase

GPR129 interaction

STRING

GPR129 Proteomic

PRIDE

GPR129 Genome annotation

Ensembl

GeneID

KEGG

UCSC

GPR129 Organism specific

CTD

MGI

GPR129 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

GPR129 Gene expression

Bgee

ArrayExpress

Genevestigator

GPR129 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY