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Human Ovarian cancer G-protein coupled receptor 1 (aa 1-365)

OGR1 Swiss Prot#

Q15743

OGR1 Protein names

Ovarian cancer G-protein coupled receptor 1 (OGR-1) (G-protein coupled receptor 68) (Sphingosylphosphorylcholine receptor) (GPR12A)

OGR1 Gene names

GPR68 OGR1

Organism

Human

OGR1 Entry name

OGR1_HUMAN

OGR1 Codon optimized cDNA(gene) Clone

OGR1 Cat #

RPX0550

Tag

OGR1 contains A 6x histidine tag

OGR1 Formulation

Liquid

OGR1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

OGR1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant OGR1 Protein

OGR1 Cat #

PX0550

OGR1 Source

recombinant

OGR1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

OGR1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

OGR1 Activity

N/A

Tag

OGR1 Contains A 6x histidine tag

OGR1 Formulation

Liquid

OGR1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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OGR1 family

G-protein coupled receptor 1 family

OGR1 Subcellular locations

Cell membrane; Multi-pass membrane protein.

OGR1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).

OGR1 Sequence

DDBJ

EMBL

GenBank

OGR1 3D structure

ModBase

OGR1 interaction

STRING

OGR1 Proteomic

PRIDE

OGR1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

OGR1 Organism specific

CTD

MGI

OGR1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

OGR1 Gene expression

Bgee

ArrayExpress

Genevestigator

OGR1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY