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Human C-C chemokine receptor type 4 (aa 1-360)

CMKBR4 Swiss Prot#

P51679

CMKBR4 Protein names

C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)

CMKBR4 Gene names

CCR4 CMKBR4

Organism

Human

CMKBR4 Entry name

CCR4_HUMAN

CMKBR4 Codon optimized cDNA(gene) Clone

CMKBR4 Cat #

RPX0530

Tag

CMKBR4 contains A 6x histidine tag

CMKBR4 Formulation

Liquid

CMKBR4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CMKBR4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CMKBR4 Protein

CMKBR4 Cat #

PX0530

CMKBR4 Source

recombinant

CMKBR4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CMKBR4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CMKBR4 Activity

N/A

Tag

CMKBR4 Contains A 6x histidine tag

CMKBR4 Formulation

Liquid

CMKBR4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CMKBR4 family

G-protein coupled receptor 1 family

CMKBR4 Subcellular locations

Cell membrane; Multi-pass membrane protein.

CMKBR4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

CMKBR4 Sequence

DDBJ

EMBL

GenBank

CMKBR4 3D structure

ModBase

CMKBR4 interaction

STRING

CMKBR4 Proteomic

PRIDE

CMKBR4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CMKBR4 Organism specific

CTD

MGI

CMKBR4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CMKBR4 Gene expression

Bgee

ArrayExpress

Genevestigator

CMKBR4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY