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Human C-X-C chemokine receptor type 1 (aa 1-350)

CMKAR1 Swiss Prot#

P25024

CMKAR1 Protein names

C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CDw128a) (CD antigen CD181)

CMKAR1 Gene names

CXCR1 CMKAR1 IL8RA

Organism

Human

CMKAR1 Entry name

CXCR1_HUMAN

CMKAR1 Codon optimized cDNA(gene) Clone

CMKAR1 Cat #

RPX0494

Tag

CMKAR1 contains A 6x histidine tag

CMKAR1 Formulation

Liquid

CMKAR1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CMKAR1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CMKAR1 Protein

CMKAR1 Cat #

PX0494

CMKAR1 Source

recombinant

CMKAR1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CMKAR1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CMKAR1 Activity

N/A

Tag

CMKAR1 Contains A 6x histidine tag

CMKAR1 Formulation

Liquid

CMKAR1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CMKAR1 family

G-protein coupled receptor 1 family

CMKAR1 Subcellular locations

Cell membrane; Multi-pass membrane protein.

CMKAR1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

CMKAR1 Sequence

DDBJ

EMBL

GenBank

CMKAR1 3D structure

ModBase

CMKAR1 interaction

STRING

CMKAR1 Proteomic

PRIDE

CMKAR1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CMKAR1 Organism specific

CTD

MGI

CMKAR1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CMKAR1 Gene expression

Bgee

ArrayExpress

Genevestigator

CMKAR1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY