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Human Trace amine-associated receptor 1 (aa 1-339)

TA1 Swiss Prot#

Q96RJ0

TA1 Protein names

Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1)

TA1 Gene names

TAAR1 TA1 TAR1 TRAR1

Organism

Human

TA1 Entry name

TAAR1_HUMAN

TA1 Codon optimized cDNA(gene) Clone

TA1 Cat #

RPX0456

Tag

TA1 contains A 6x histidine tag

TA1 Formulation

Liquid

TA1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TA1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TA1 Protein

TA1 Cat #

PX0456

TA1 Source

recombinant

TA1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TA1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TA1 Activity

N/A

Tag

TA1 Contains A 6x histidine tag

TA1 Formulation

Liquid

TA1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TA1 family

G-protein coupled receptor 1 family

TA1 Subcellular locations

Cell membrane; Multi-pass membrane protein.

TA1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.

TA1 Sequence

DDBJ

EMBL

GenBank

TA1 3D structure

ModBase

TA1 interaction

STRING

TA1 Proteomic

PRIDE

TA1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TA1 Organism specific

CTD

MGI

TA1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TA1 Gene expression

Bgee

ArrayExpress

Genevestigator

TA1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY