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Human Cysteinyl leukotriene receptor 1 (aa -337)

CYSLT1 Swiss Prot#

Q9Y271

CYSLT1 Protein names

Cysteinyl leukotriene receptor 1 (CysLTR1) (Cysteinyl leukotriene D4 receptor) (LTD4 receptor) (G-protein coupled receptor HG55) (HMTMF81)

CYSLT1 Gene names

CYSLTR1 CYSLT1

Organism

Human

CYSLT1 Entry name

CLTR1_HUMAN

CYSLT1 Codon optimized cDNA(gene) Clone

CYSLT1 Cat #

RPX0446

Tag

CYSLT1 contains A 6x histidine tag

CYSLT1 Formulation

Liquid

CYSLT1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYSLT1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYSLT1 Protein

CYSLT1 Cat #

PX0446

CYSLT1 Source

recombinant

CYSLT1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYSLT1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYSLT1 Activity

N/A

Tag

CYSLT1 Contains A 6x histidine tag

CYSLT1 Formulation

Liquid

CYSLT1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYSLT1 family

G-protein coupled receptor 1 family

CYSLT1 Subcellular locations

Cell membrane; Multi-pass membrane protein.

CYSLT1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

CYSLT1 Sequence

DDBJ

EMBL

GenBank

CYSLT1 3D structure

ModBase

CYSLT1 interaction

STRING

CYSLT1 Proteomic

PRIDE

CYSLT1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYSLT1 Organism specific

CTD

MGI

CYSLT1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYSLT1 Gene expression

Bgee

ArrayExpress

Genevestigator

CYSLT1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY