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Human Mas-related G-protein coupled receptor X2 (aa 1-330)
MRGX2 Swiss Prot#
Q96LB1
MRGX2 Protein names
Mas-related G-protein coupled receptor member X2
MRGX2 Gene names
MRGPRX2 MRGX2
Organism
Human
MRGX2 Entry name
MRGX2_HUMAN
MRGX2 Codon optimized cDNA(gene) Clone
MRGX2 Cat #
RPX0418
Tag
MRGX2 contains A 6x histidine tag
MRGX2 Formulation
Liquid
MRGX2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
MRGX2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant MRGX2 Protein
MRGX2 Cat #
PX0418
MRGX2 Source
recombinant
MRGX2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
MRGX2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
MRGX2 Activity
N/A
Tag
MRGX2 Contains A 6x histidine tag
MRGX2 Formulation
Liquid
MRGX2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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MRGX2 family
G-protein coupled receptor 1 family, Mas subfamily
MRGX2 Subcellular locations
Cell membrane; Multi-pass membrane protein.
MRGX2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
MRGX2 Sequence
DDBJ EMBL GenBank
MRGX2 3D structure
ModBase
MRGX2 interaction
STRING
MRGX2 Proteomic
PRIDE
MRGX2 Genome annotation
Ensembl GeneID KEGG UCSC
MRGX2 Organism specific
CTD MGI
MRGX2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MRGX2 Gene expression
Bgee ArrayExpress Genevestigator
MRGX2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY