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| Human Mas-related G-protein coupled receptor X2 (aa 1-330) |
| MRGX2 Swiss Prot# | | Q96LB1 |
| MRGX2 Protein names | | Mas-related G-protein coupled receptor member X2 |
| MRGX2 Gene names | | MRGPRX2 MRGX2 |
| Organism | | Human |
| MRGX2 Entry name | | MRGX2_HUMAN |
| MRGX2 Codon optimized cDNA(gene) Clone |
| MRGX2 Cat # | | RPX0418 |
| Tag | | MRGX2 contains A 6x histidine tag |
| MRGX2 Formulation | | Liquid |
| MRGX2 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| MRGX2 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant MRGX2 Protein |
| MRGX2 Cat # | | PX0418 |
| MRGX2 Source | | recombinant |
| MRGX2 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| MRGX2 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| MRGX2 Activity | | N/A |
| Tag | | MRGX2 Contains A 6x histidine tag |
| MRGX2 Formulation | | Liquid |
| MRGX2 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant MRGX2 Products | | For pricing and availability Click Here >>> |
| MRGX2 family | | G-protein coupled receptor 1 family, Mas subfamily |
| MRGX2 Subcellular locations | | Cell membrane; Multi-pass membrane protein. |
| MRGX2 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. |
| MRGX2 Sequence | | DDBJ | EMBL | GenBank |
| MRGX2 3D structure | | ModBase |
| MRGX2 interaction | | STRING |
| MRGX2 Proteomic | | PRIDE |
| MRGX2 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| MRGX2 Organism specific | | CTD | MGI |
| MRGX2 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| MRGX2 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| MRGX2 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |