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Human Mas-related G-protein coupled receptor X1 (aa 1-322)

MRGX1 Swiss Prot#

Q96LB2

MRGX1 Protein names

Mas-related G-protein coupled receptor member X1 (Sensory neuron-specific G-protein coupled receptor 3/4)

MRGX1 Gene names

MRGPRX1 MRGX1 SNSR3 SNSR4

Organism

Human

MRGX1 Entry name

MRGX1_HUMAN

MRGX1 Codon optimized cDNA(gene) Clone

MRGX1 Cat #

RPX0359

Tag

MRGX1 contains A 6x histidine tag

MRGX1 Formulation

Liquid

MRGX1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MRGX1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MRGX1 Protein

MRGX1 Cat #

PX0359

MRGX1 Source

recombinant

MRGX1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MRGX1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MRGX1 Activity

N/A

Tag

MRGX1 Contains A 6x histidine tag

MRGX1 Formulation

Liquid

MRGX1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MRGX1 family

G-protein coupled receptor 1 family, Mas subfamily

MRGX1 Subcellular locations

Cell membrane; Multi-pass membrane protein.

MRGX1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in an histamine-independent manner.

MRGX1 Sequence

DDBJ

EMBL

GenBank

MRGX1 3D structure

ModBase

MRGX1 interaction

STRING

MRGX1 Proteomic

PRIDE

MRGX1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MRGX1 Organism specific

CTD

MGI

MRGX1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MRGX1 Gene expression

Bgee

ArrayExpress

Genevestigator

MRGX1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY