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Human Estrogen receptor beta (aa 1-530)

ESTRB Swiss Prot#

Q92731

ESTRB Protein names

Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)

ESTRB Gene names

ESR2 (ESTRB) (NR3A2)

Organism

Human

ESTRB Entry name

ESR2_HUMAN

ESTRB Codon optimized cDNA(gene) Clone

ESTRB Cat #

RPR0593

Tag

ESTRB contains A 6x histidine tag

ESTRB Formulation

Liquid

ESTRB Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ESTRB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ESTRB Protein

ESTRB Cat #

PR0593

ESTRB Source

recombinant

ESTRB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ESTRB Purity

>90%, as determined by SDS-PAGE under reducing conditions

ESTRB Activity

N/A

Tag

ESTRB Contains A 6x histidine tag

ESTRB Formulation

Liquid

ESTRB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ESTRB family

Nuclear hormone receptor family, NR3 subfamily

ESTRB Subcellular locations

Nucleus.

ESTRB FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

ESTRB Sequence

DDBJ

EMBL

GenBank

ESTRB 3D structure

ModBase

ESTRB interaction

STRING

ESTRB Proteomic

PRIDE

ESTRB Genome annotation

Ensembl

GeneID

KEGG

UCSC

ESTRB Organism specific

CTD

MGI

ESTRB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ESTRB Gene expression

Bgee

ArrayExpress

Genevestigator

ESTRB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY