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Human Protein BANP (aa 1-519)

BEND1 Swiss Prot#

Q8N9N5

BEND1 Protein names

Protein BANP (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein) (BEN domain-containing protein 1)

BEND1 Gene names

BANP (BEND1) (SMAR1)

Organism

Human

BEND1 Entry name

BANP_HUMAN

BEND1 Codon optimized cDNA(gene) Clone

BEND1 Cat #

RPR0588

Tag

BEND1 contains A 6x histidine tag

BEND1 Formulation

Liquid

BEND1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

BEND1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant BEND1 Protein

BEND1 Cat #

PR0588

BEND1 Source

recombinant

BEND1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

BEND1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

BEND1 Activity

N/A

Tag

BEND1 Contains A 6x histidine tag

BEND1 Formulation

Liquid

BEND1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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BEND1 family

BANP/SMAR1 family

BEND1 Subcellular locations

Nucleus.

BEND1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

BEND1 Sequence

DDBJ

EMBL

GenBank

BEND1 3D structure

ModBase

BEND1 interaction

STRING

BEND1 Proteomic

PRIDE

BEND1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

BEND1 Organism specific

CTD

MGI

BEND1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BEND1 Gene expression

Bgee

ArrayExpress

Genevestigator

BEND1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY