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Human TERF1-interacting nuclear factor 2 (aa 1-451)

TIN2 Swiss Prot#

Q9BSI4

TIN2 Protein names

TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2)

TIN2 Gene names

TINF2 (TIN2)

Organism

Human

TIN2 Entry name

TINF2_HUMAN

TIN2 Codon optimized cDNA(gene) Clone

TIN2 Cat #

RPR0544

Tag

TIN2 contains A 6x histidine tag

TIN2 Formulation

Liquid

TIN2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TIN2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TIN2 Protein

TIN2 Cat #

PR0544

TIN2 Source

recombinant

TIN2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TIN2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TIN2 Activity

N/A

Tag

TIN2 Contains A 6x histidine tag

TIN2 Formulation

Liquid

TIN2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TIN2 family

-

TIN2 Subcellular locations

Nucleus. Chromosome > telomere.

TIN2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.

TIN2 Sequence

DDBJ

EMBL

GenBank

TIN2 3D structure

ModBase

TIN2 interaction

STRING

TIN2 Proteomic

PRIDE

TIN2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TIN2 Organism specific

CTD

MGI

TIN2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TIN2 Gene expression

Bgee

ArrayExpress

Genevestigator

TIN2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY