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Human Heterogeneous nuclear ribonucleoprotein D-like (aa 1-420)

JKTBP Swiss Prot#

O14979

JKTBP Protein names

Heterogeneous nuclear ribonucleoprotein D-like (hnRPD-like protein) (hnHNRP-DL) (JKT41-binding protein) (AU-rich element RNA-binding factor) (Protein laAUF1)

JKTBP Gene names

HNRPDL (JKTBP)

Organism

Human

JKTBP Entry name

HNRDL_HUMAN

JKTBP Codon optimized cDNA(gene) Clone

JKTBP Cat #

RPR0524

Tag

JKTBP contains A 6x histidine tag

JKTBP Formulation

Liquid

JKTBP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

JKTBP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant JKTBP Protein

JKTBP Cat #

PR0524

JKTBP Source

recombinant

JKTBP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

JKTBP Purity

>90%, as determined by SDS-PAGE under reducing conditions

JKTBP Activity

N/A

Tag

JKTBP Contains A 6x histidine tag

JKTBP Formulation

Liquid

JKTBP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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JKTBP family

-

JKTBP Subcellular locations

Nucleus. Cytoplasm.

JKTBP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence.

JKTBP Sequence

DDBJ

EMBL

GenBank

JKTBP 3D structure

ModBase

JKTBP interaction

STRING

JKTBP Proteomic

PRIDE

JKTBP Genome annotation

Ensembl

GeneID

KEGG

UCSC

JKTBP Organism specific

CTD

MGI

JKTBP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

JKTBP Gene expression

Bgee

ArrayExpress

Genevestigator

JKTBP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY