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Human Centromere protein U (aa 1-418)

CENPU Swiss Prot#

Q71F23

CENPU Protein names

Centromere protein U (CENP-U(50)) (CENP-U) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1) (Polo-box-interacting protein 1)

CENPU Gene names

MLF1IP (CENPU) (ICEN24) (KLIP1) (PBIP1)

Organism

Human

CENPU Entry name

CENPU_HUMAN

CENPU Codon optimized cDNA(gene) Clone

CENPU Cat #

RPR0521

Tag

CENPU contains A 6x histidine tag

CENPU Formulation

Liquid

CENPU Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CENPU Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CENPU Protein

CENPU Cat #

PR0521

CENPU Source

recombinant

CENPU Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CENPU Purity

>90%, as determined by SDS-PAGE under reducing conditions

CENPU Activity

N/A

Tag

CENPU Contains A 6x histidine tag

CENPU Formulation

Liquid

CENPU Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CENPU family

-

CENPU Subcellular locations

Cytoplasm. Nucleus. Chromosome > centromere > kinetochore.

CENPU FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.

CENPU Sequence

DDBJ

EMBL

GenBank

CENPU 3D structure

ModBase

CENPU interaction

STRING

CENPU Proteomic

PRIDE

CENPU Genome annotation

Ensembl

GeneID

KEGG

UCSC

CENPU Organism specific

CTD

MGI

CENPU Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CENPU Gene expression

Bgee

ArrayExpress

Genevestigator

CENPU Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY