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Human Transforming growth factor beta regulator 1 (aa 1-411)

NIAM Swiss Prot#

Q3YBR2

NIAM Protein names

Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)

NIAM Gene names

TBRG1 (NIAM)

Organism

Human

NIAM Entry name

TBRG1_HUMAN

NIAM Codon optimized cDNA(gene) Clone

NIAM Cat #

RPR0516

Tag

NIAM contains A 6x histidine tag

NIAM Formulation

Liquid

NIAM Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NIAM Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NIAM Protein

NIAM Cat #

PR0516

NIAM Source

recombinant

NIAM Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NIAM Purity

>90%, as determined by SDS-PAGE under reducing conditions

NIAM Activity

N/A

Tag

NIAM Contains A 6x histidine tag

NIAM Formulation

Liquid

NIAM Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NIAM family

TBRG1 family

NIAM Subcellular locations

Nucleus.

NIAM FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.

NIAM Sequence

DDBJ

EMBL

GenBank

NIAM 3D structure

ModBase

NIAM interaction

STRING

NIAM Proteomic

PRIDE

NIAM Genome annotation

Ensembl

GeneID

KEGG

UCSC

NIAM Organism specific

CTD

MGI

NIAM Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NIAM Gene expression

Bgee

ArrayExpress

Genevestigator

NIAM Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY