|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Human Photoreceptor-specific nuclear receptor (aa 1-410) |
| PNR Swiss Prot# | | Q9Y5X4 |
| PNR Protein names | | Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor) (Nuclear receptor subfamily 2 group E member 3) |
| PNR Gene names | | NR2E3 (PNR) (RNR) |
| Organism | | Human |
| PNR Entry name | | NR2E3_HUMAN |
| PNR Codon optimized cDNA(gene) Clone |
| PNR Cat # | | RPR0514 |
| Tag | | PNR contains A 6x histidine tag |
| PNR Formulation | | Liquid |
| PNR Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| PNR Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant PNR Protein |
| PNR Cat # | | PR0514 |
| PNR Source | | recombinant |
| PNR Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| PNR Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| PNR Activity | | N/A |
| Tag | | PNR Contains A 6x histidine tag |
| PNR Formulation | | Liquid |
| PNR Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant PNR Products | | For pricing and availability Click Here >>> |
| PNR family | | Nuclear hormone receptor family, NR2 subfamily |
| PNR Subcellular locations | | Nucleus. |
| PNR FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression. |
| PNR Sequence | | DDBJ | EMBL | GenBank |
| PNR 3D structure | | ModBase |
| PNR interaction | | STRING |
| PNR Proteomic | | PRIDE |
| PNR Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| PNR Organism specific | | CTD | MGI |
| PNR Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| PNR Gene expression | | Bgee | ArrayExpress | Genevestigator |
| PNR Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |