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Human CTD small phosphatase-like protein (aa 1-276)

C3orf8 Swiss Prot#

O15194

C3orf8 Protein names

CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.-) (Small C-terminal domain phosphatase 3) (Small CTD phosphatase 3) (SCP3) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (NIF-like protein) (RBSP3) (Protein YA22) (hYA22)

C3orf8 Gene names

CTDSPL (C3orf8) (NIF1) (NIFL) (SCP3) (YA22)

Organism

Human

C3orf8 Entry name

CTDSL_HUMAN

C3orf8 Codon optimized cDNA(gene) Clone

C3orf8 Cat #

RPR0433

Tag

C3orf8 contains A 6x histidine tag

C3orf8 Formulation

Liquid

C3orf8 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

C3orf8 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant C3orf8 Protein

C3orf8 Cat #

PR0433

C3orf8 Source

recombinant

C3orf8 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

C3orf8 Purity

>90%, as determined by SDS-PAGE under reducing conditions

C3orf8 Activity

N/A

Tag

C3orf8 Contains A 6x histidine tag

C3orf8 Formulation

Liquid

C3orf8 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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C3orf8 family

-

C3orf8 Subcellular locations

Nucleus.

C3orf8 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

C3orf8 Sequence

DDBJ

EMBL

GenBank

C3orf8 3D structure

ModBase

C3orf8 interaction

STRING

C3orf8 Proteomic

PRIDE

C3orf8 Genome annotation

Ensembl

GeneID

KEGG

UCSC

C3orf8 Organism specific

CTD

MGI

C3orf8 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

C3orf8 Gene expression

Bgee

ArrayExpress

Genevestigator

C3orf8 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY