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Human Carboxy-terminal domain RNA polymerase II 1 (aa 1-261)

NIF3 Swiss Prot#

Q9GZU7

NIF3 Protein names

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-interacting factor 3) (NLI-IF)

NIF3 Gene names

CTDSP1 (NIF3) (NLIIF) (SCP1)

Organism

Human

NIF3 Entry name

CTDS1_HUMAN

NIF3 Codon optimized cDNA(gene) Clone

NIF3 Cat #

RPR0426

Tag

NIF3 contains A 6x histidine tag

NIF3 Formulation

Liquid

NIF3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NIF3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NIF3 Protein

NIF3 Cat #

PR0426

NIF3 Source

recombinant

NIF3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NIF3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NIF3 Activity

N/A

Tag

NIF3 Contains A 6x histidine tag

NIF3 Formulation

Liquid

NIF3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NIF3 family

-

NIF3 Subcellular locations

Nucleus.

NIF3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

NIF3 Sequence

DDBJ

EMBL

GenBank

NIF3 3D structure

ModBase

NIF3 interaction

STRING

NIF3 Proteomic

PRIDE

NIF3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NIF3 Organism specific

CTD

MGI

NIF3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NIF3 Gene expression

Bgee

ArrayExpress

Genevestigator

NIF3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY