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Human Splicing factor U2AF 26 kDa subunit (aa 2-220)

U2AF1-RS3 Swiss Prot#

Q8WU68

U2AF1-RS3 Protein names

Splicing factor U2AF 26 kDa subunit (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3) (U2 small nuclear RNA auxiliary factor 1-like protein 3) (U2AF1-like protein 3)

U2AF1-RS3 Gene names

U2AF1L4 (U2AF1-RS3) (U2AF1L3)

Organism

Human

U2AF1-RS3 Entry name

U2AF4_HUMAN

U2AF1-RS3 Codon optimized cDNA(gene) Clone

U2AF1-RS3 Cat #

RPR0391

Tag

U2AF1-RS3 contains A 6x histidine tag

U2AF1-RS3 Formulation

Liquid

U2AF1-RS3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

U2AF1-RS3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant U2AF1-RS3 Protein

U2AF1-RS3 Cat #

PR0391

U2AF1-RS3 Source

recombinant

U2AF1-RS3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

U2AF1-RS3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

U2AF1-RS3 Activity

N/A

Tag

U2AF1-RS3 Contains A 6x histidine tag

U2AF1-RS3 Formulation

Liquid

U2AF1-RS3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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U2AF1-RS3 family

Splicing factor SR family

U2AF1-RS3 Subcellular locations

Nucleus. Nucleus speckle.

U2AF1-RS3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity).

U2AF1-RS3 Sequence

DDBJ

EMBL

GenBank

U2AF1-RS3 3D structure

ModBase

U2AF1-RS3 interaction

STRING

U2AF1-RS3 Proteomic

PRIDE

U2AF1-RS3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

U2AF1-RS3 Organism specific

CTD

MGI

U2AF1-RS3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

U2AF1-RS3 Gene expression

Bgee

ArrayExpress

Genevestigator

U2AF1-RS3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY