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Human Homologous-pairing protein 2 homolog (aa 1-217)

HOP2 Swiss Prot#

Q9P2W1

HOP2 Protein names

Homologous-pairing protein 2 homolog (Proteasome 26S ATPase subunit 3-interacting protein) (PSMC3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein) (Nuclear receptor coactivator GT198)

HOP2 Gene names

PSMC3IP (HOP2) (TBPIP)

Organism

Human

HOP2 Entry name

HOP2_HUMAN

HOP2 Codon optimized cDNA(gene) Clone

HOP2 Cat #

RPR0388

Tag

HOP2 contains A 6x histidine tag

HOP2 Formulation

Liquid

HOP2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

HOP2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant HOP2 Protein

HOP2 Cat #

PR0388

HOP2 Source

recombinant

HOP2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

HOP2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

HOP2 Activity

N/A

Tag

HOP2 Contains A 6x histidine tag

HOP2 Formulation

Liquid

HOP2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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HOP2 family

HOP2 family

HOP2 Subcellular locations

Nucleus.

HOP2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

HOP2 Sequence

DDBJ

EMBL

GenBank

HOP2 3D structure

ModBase

HOP2 interaction

STRING

HOP2 Proteomic

PRIDE

HOP2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

HOP2 Organism specific

CTD

MGI

HOP2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

HOP2 Gene expression

Bgee

ArrayExpress

Genevestigator

HOP2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY