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Human GTP-binding nuclear protein Ran (aa 2-216)

ARA24 Swiss Prot#

P62826

ARA24 Protein names

GTP-binding nuclear protein Ran (GTPase Ran) (Ras-related nuclear protein) (Ras-like protein TC4) (Androgen receptor-associated protein 24)

ARA24 Gene names

RAN (ARA24) (OK/SW-cl.81)

Organism

Human

ARA24 Entry name

RAN_HUMAN

ARA24 Codon optimized cDNA(gene) Clone

ARA24 Cat #

RPR0386

Tag

ARA24 contains A 6x histidine tag

ARA24 Formulation

Liquid

ARA24 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ARA24 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ARA24 Protein

ARA24 Cat #

PR0386

ARA24 Source

recombinant

ARA24 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ARA24 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ARA24 Activity

N/A

Tag

ARA24 Contains A 6x histidine tag

ARA24 Formulation

Liquid

ARA24 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ARA24 family

Small GTPase superfamily, Ran family

ARA24 Subcellular locations

Nucleus. Cytoplasm. Melanosome.

ARA24 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.; FUNCTION: Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.

ARA24 Sequence

DDBJ

EMBL

GenBank

ARA24 3D structure

ModBase

ARA24 interaction

STRING

ARA24 Proteomic

PRIDE

ARA24 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ARA24 Organism specific

CTD

MGI

ARA24 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ARA24 Gene expression

Bgee

ArrayExpress

Genevestigator

ARA24 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY