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Rat Cellular tumor antigen p53 (aa 1-391)

P53 Swiss Prot#

P10361

P53 Protein names

Cellular tumor antigen p53 (Tumor suppressor p53)

P53 Gene names

Tp53 (P53)

Organism

Rat

P53 Entry name

P53_RAT

P53 Codon optimized cDNA(gene) Clone

P53 Cat #

RPR0291

Tag

P53 contains A 6x histidine tag

P53 Formulation

Liquid

P53 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

P53 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant P53 Protein

P53 Cat #

PR0291

P53 Source

recombinant

P53 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

P53 Purity

>90%, as determined by SDS-PAGE under reducing conditions

P53 Activity

N/A

Tag

P53 Contains A 6x histidine tag

P53 Formulation

Liquid

P53 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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P53 family

P53 family

P53 Subcellular locations

Cytoplasm. Nucleus. Endoplasmic reticulum.

P53 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.

P53 Sequence

DDBJ

EMBL

GenBank

P53 3D structure

ModBase

P53 interaction

STRING

P53 Proteomic

PRIDE

P53 Genome annotation

Ensembl

GeneID

KEGG

UCSC

P53 Organism specific

CTD

MGI

P53 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

P53 Gene expression

Bgee

ArrayExpress

Genevestigator

P53 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY