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Rat DnaJ homolog subfamily B member 6 (aa 2-357)

Dnajb6 Swiss Prot#

Q6AYU3

Dnajb6 Protein names

DnaJ homolog subfamily B member 6 (Heat shock protein J2) (HSJ-2) (MSJ-1) (Hsp40 homolog) (MRJ)

Dnajb6 Gene names

Dnajb6

Organism

Rat

Dnajb6 Entry name

DNJB6_RAT

Dnajb6 Codon optimized cDNA(gene) Clone

Dnajb6 Cat #

RPR0287

Tag

Dnajb6 contains A 6x histidine tag

Dnajb6 Formulation

Liquid

Dnajb6 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dnajb6 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dnajb6 Protein

Dnajb6 Cat #

PR0287

Dnajb6 Source

recombinant

Dnajb6 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dnajb6 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dnajb6 Activity

N/A

Tag

Dnajb6 Contains A 6x histidine tag

Dnajb6 Formulation

Liquid

Dnajb6 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dnajb6 family

-

Dnajb6 Subcellular locations

Cytoplasm > perinuclear region. Nucleus.

Dnajb6 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including the Huntington's disease (HD) protein. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Reduces polyglutamine protein (huntingtin) aggregation associated with HD. Also reduces cellular toxicity and caspase-3 activity (By similarity).

Dnajb6 Sequence

DDBJ

EMBL

GenBank

Dnajb6 3D structure

ModBase

Dnajb6 interaction

STRING

Dnajb6 Proteomic

PRIDE

Dnajb6 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dnajb6 Organism specific

CTD

MGI

Dnajb6 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dnajb6 Gene expression

Bgee

ArrayExpress

Genevestigator

Dnajb6 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY