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Rat Cyclin-dependent kinase inhibitor 2A isoform 1 (aa 1-159)
P16ink4a Swiss Prot#
Q9R0Z3
P16ink4a Protein names
Cyclin-dependent kinase inhibitor 2A, isoform 1 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4a) (p16-INK4) (p16)
P16ink4a Gene names
Cdkn2a (P16ink4a)
Organism
Rat
P16ink4a Entry name
CD2A1_RAT
P16ink4a Codon optimized cDNA(gene) Clone
P16ink4a Cat #
RPR0266
Tag
P16ink4a contains A 6x histidine tag
P16ink4a Formulation
Liquid
P16ink4a Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
P16ink4a Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant P16ink4a Protein
P16ink4a Cat #
PR0266
P16ink4a Source
recombinant
P16ink4a Applications
Western Blot, SDS-Page or may be used for other applications determined by user
P16ink4a Purity
>90%, as determined by SDS-PAGE under reducing conditions
P16ink4a Activity
N/A
Tag
P16ink4a Contains A 6x histidine tag
P16ink4a Formulation
Liquid
P16ink4a Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant P16ink4a Products
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P16ink4a family
CDKN2 cyclin-dependent kinase inhibitor family
P16ink4a Subcellular locations
Cytoplasm. Nucleus.
P16ink4a FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein (By similarity).
P16ink4a Sequence
DDBJ EMBL GenBank
P16ink4a 3D structure
ModBase
P16ink4a interaction
STRING
P16ink4a Proteomic
PRIDE
P16ink4a Genome annotation
Ensembl GeneID KEGG UCSC
P16ink4a Organism specific
CTD MGI
P16ink4a Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
P16ink4a Gene expression
Bgee ArrayExpress Genevestigator
P16ink4a Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY