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| Rat Cyclin-dependent kinase inhibitor 2A isoform 1 (aa 1-159) |
| P16ink4a Swiss Prot# | | Q9R0Z3 |
| P16ink4a Protein names | | Cyclin-dependent kinase inhibitor 2A, isoform 1 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4a) (p16-INK4) (p16) |
| P16ink4a Gene names | | Cdkn2a (P16ink4a) |
| Organism | | Rat |
| P16ink4a Entry name | | CD2A1_RAT |
| P16ink4a Codon optimized cDNA(gene) Clone |
| P16ink4a Cat # | | RPR0266 |
| Tag | | P16ink4a contains A 6x histidine tag |
| P16ink4a Formulation | | Liquid |
| P16ink4a Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| P16ink4a Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant P16ink4a Protein |
| P16ink4a Cat # | | PR0266 |
| P16ink4a Source | | recombinant |
| P16ink4a Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| P16ink4a Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| P16ink4a Activity | | N/A |
| Tag | | P16ink4a Contains A 6x histidine tag |
| P16ink4a Formulation | | Liquid |
| P16ink4a Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant P16ink4a Products | | For pricing and availability Click Here >>> |
| P16ink4a family | | CDKN2 cyclin-dependent kinase inhibitor family |
| P16ink4a Subcellular locations | | Cytoplasm. Nucleus. |
| P16ink4a FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein (By similarity). |
| P16ink4a Sequence | | DDBJ | EMBL | GenBank |
| P16ink4a 3D structure | | ModBase |
| P16ink4a interaction | | STRING |
| P16ink4a Proteomic | | PRIDE |
| P16ink4a Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| P16ink4a Organism specific | | CTD | MGI |
| P16ink4a Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| P16ink4a Gene expression | | Bgee | ArrayExpress | Genevestigator |
| P16ink4a Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |