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Rat Homeodomain-only protein (aa 1-73)

Giig15b Swiss Prot#

Q78ZR5

Giig15b Protein names

Homeodomain-only protein (Odd homeobox protein 1) (Global ischemia-induced protein 15B) (GIIg15b)

Giig15b Gene names

Hopx (Giig15b) (Hod) (Hop) (Ob1)

Organism

Rat

Giig15b Entry name

HOP_RAT

Giig15b Codon optimized cDNA(gene) Clone

Giig15b Cat #

RPR0263

Tag

Giig15b contains A 6x histidine tag

Giig15b Formulation

Liquid

Giig15b Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Giig15b Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Giig15b Protein

Giig15b Cat #

PR0263

Giig15b Source

recombinant

Giig15b Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Giig15b Purity

>90%, as determined by SDS-PAGE under reducing conditions

Giig15b Activity

N/A

Tag

Giig15b Contains A 6x histidine tag

Giig15b Formulation

Liquid

Giig15b Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Giig15b family

-

Giig15b Subcellular locations

Nucleus.

Giig15b FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity).

Giig15b Sequence

DDBJ

EMBL

GenBank

Giig15b 3D structure

ModBase

Giig15b interaction

STRING

Giig15b Proteomic

PRIDE

Giig15b Genome annotation

Ensembl

GeneID

KEGG

UCSC

Giig15b Organism specific

CTD

MGI

Giig15b Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Giig15b Gene expression

Bgee

ArrayExpress

Genevestigator

Giig15b Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY