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Mouse Cytochrome P450 8B1 (aa 1-500)

Cyp12 Swiss Prot#

O88962

Cyp12 Protein names

Cytochrome P450 8B1 (EC 1.14.13.95) (CYPVIIIB1) (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (Sterol 12-alpha-hydroxylase)

Cyp12 Gene names

Cyp8b1 (Cyp12)

Organism

Mouse

Cyp12 Entry name

CP8B1_MOUSE

Cyp12 Codon optimized cDNA(gene) Clone

Cyp12 Cat #

RPR0222

Tag

Cyp12 contains A 6x histidine tag

Cyp12 Formulation

Liquid

Cyp12 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cyp12 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cyp12 Protein

Cyp12 Cat #

PR0222

Cyp12 Source

recombinant

Cyp12 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cyp12 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cyp12 Activity

N/A

Tag

Cyp12 Contains A 6x histidine tag

Cyp12 Formulation

Liquid

Cyp12 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cyp12 family

Cytochrome P450 family

Cyp12 Subcellular locations

Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.

Cyp12 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.

Cyp12 Sequence

DDBJ

EMBL

GenBank

Cyp12 3D structure

ModBase

Cyp12 interaction

STRING

Cyp12 Proteomic

PRIDE

Cyp12 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cyp12 Organism specific

CTD

MGI

Cyp12 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cyp12 Gene expression

Bgee

ArrayExpress

Genevestigator

Cyp12 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY