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Mouse Estradiol 17-beta-dehydrogenase 2 (aa 1-381)

Edh17b2 Swiss Prot#

P51658

Edh17b2 Protein names

Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.63) (17-beta-hydroxysteroid dehydrogenase 2) (17-beta-HSD 2)

Edh17b2 Gene names

Hsd17b2 (Edh17b2)

Organism

Mouse

Edh17b2 Entry name

DHB2_MOUSE

Edh17b2 Codon optimized cDNA(gene) Clone

Edh17b2 Cat #

RPR0185

Tag

Edh17b2 contains A 6x histidine tag

Edh17b2 Formulation

Liquid

Edh17b2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Edh17b2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Edh17b2 Protein

Edh17b2 Cat #

PR0185

Edh17b2 Source

recombinant

Edh17b2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Edh17b2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Edh17b2 Activity

N/A

Tag

Edh17b2 Contains A 6x histidine tag

Edh17b2 Formulation

Liquid

Edh17b2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Edh17b2 family

Short-chain dehydrogenases/reductases (SDR) family

Edh17b2 Subcellular locations

Membrane; Single-pass type II membrane protein.

Edh17b2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH (By similarity).

Edh17b2 Sequence

DDBJ

EMBL

GenBank

Edh17b2 3D structure

ModBase

Edh17b2 interaction

STRING

Edh17b2 Proteomic

PRIDE

Edh17b2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Edh17b2 Organism specific

CTD

MGI

Edh17b2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Edh17b2 Gene expression

Bgee

ArrayExpress

Genevestigator

Edh17b2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY