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Mouse Transcription factor MafB (aa 1-323)

Krml Swiss Prot#

P54841

Krml Protein names

Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor Maf-1) (Segmentation protein Kr) (Kreisler)

Krml Gene names

Mafb (Krml) (Maf1)

Organism

Mouse

Krml Entry name

MAFB_MOUSE

Krml Codon optimized cDNA(gene) Clone

Krml Cat #

RPR0173

Tag

Krml contains A 6x histidine tag

Krml Formulation

Liquid

Krml Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Krml Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Krml Protein

Krml Cat #

PR0173

Krml Source

recombinant

Krml Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Krml Purity

>90%, as determined by SDS-PAGE under reducing conditions

Krml Activity

N/A

Tag

Krml Contains A 6x histidine tag

Krml Formulation

Liquid

Krml Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Krml family

BZIP family, Maf subfamily

Krml Subcellular locations

Nucleus.

Krml FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter. Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

Krml Sequence

DDBJ

EMBL

GenBank

Krml 3D structure

ModBase

Krml interaction

STRING

Krml Proteomic

PRIDE

Krml Genome annotation

Ensembl

GeneID

KEGG

UCSC

Krml Organism specific

CTD

MGI

Krml Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Krml Gene expression

Bgee

ArrayExpress

Genevestigator

Krml Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY