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Human Carboxylesterase 2 (aa 27-559)
ICE Swiss Prot#
O00748
ICE Protein names
Carboxylesterase 2 (CE-2) (hCE-2) (EC 3.1.1.1)
ICE Gene names
CES2 (ICE)
Organism
Human
ICE Entry name
EST2_HUMAN
ICE Codon optimized cDNA(gene) Clone
ICE Cat #
RPR0113
Tag
ICE contains A 6x histidine tag
ICE Formulation
Liquid
ICE Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
ICE Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant ICE Protein
ICE Cat #
PR0113
ICE Source
recombinant
ICE Applications
Western Blot, SDS-Page or may be used for other applications determined by user
ICE Purity
>90%, as determined by SDS-PAGE under reducing conditions
ICE Activity
N/A
Tag
ICE Contains A 6x histidine tag
ICE Formulation
Liquid
ICE Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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ICE family
Type-B carboxylesterase/lipase family
ICE Subcellular locations
Endoplasmic reticulum lumen.
ICE FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine.
ICE Sequence
DDBJ EMBL GenBank
ICE 3D structure
ModBase
ICE interaction
STRING
ICE Proteomic
PRIDE
ICE Genome annotation
Ensembl GeneID KEGG UCSC
ICE Organism specific
CTD MGI
ICE Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ICE Gene expression
Bgee ArrayExpress Genevestigator
ICE Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY