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Human UDP-glucuronosyltransferase 1-4 (aa 29-534)

GNT1 Swiss Prot#

P22310

GNT1 Protein names

UDP-glucuronosyltransferase 1-4 (EC 2.4.1.17) (UDP-glucuronosyltransferase 1A4) (UDPGT) (UGT1*4) (UGT1-04) (UGT1.4) (UGT-1D) (UGT1D) (Bilirubin-specific UDPGT isozyme 2) (HUG-BR2)

GNT1 Gene names

UGT1A4 (GNT1) (UGT1)

Organism

Human

GNT1 Entry name

UD14_HUMAN

GNT1 Codon optimized cDNA(gene) Clone

GNT1 Cat #

RPR0107

Tag

GNT1 contains A 6x histidine tag

GNT1 Formulation

Liquid

GNT1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

GNT1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant GNT1 Protein

GNT1 Cat #

PR0107

GNT1 Source

recombinant

GNT1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

GNT1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

GNT1 Activity

N/A

Tag

GNT1 Contains A 6x histidine tag

GNT1 Formulation

Liquid

GNT1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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GNT1 family

UDP-glycosyltransferase family

GNT1 Subcellular locations

Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.

GNT1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate.

GNT1 Sequence

DDBJ

EMBL

GenBank

GNT1 3D structure

ModBase

GNT1 interaction

STRING

GNT1 Proteomic

PRIDE

GNT1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

GNT1 Organism specific

CTD

MGI

GNT1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

GNT1 Gene expression

Bgee

ArrayExpress

Genevestigator

GNT1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY