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Human Cytochrome P450 2A6 (aa 1-494)

CYP2A3 Swiss Prot#

P11509

CYP2A3 Protein names

Cytochrome P450 2A6 (EC 1.14.14.1) (CYPIIA6) (Coumarin 7-hydroxylase) (P450 IIA3) (CYP2A3) (P450(I))

CYP2A3 Gene names

CYP2A6 (CYP2A3)

Organism

Human

CYP2A3 Entry name

CP2A6_HUMAN

CYP2A3 Codon optimized cDNA(gene) Clone

CYP2A3 Cat #

RPR0101

Tag

CYP2A3 contains A 6x histidine tag

CYP2A3 Formulation

Liquid

CYP2A3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYP2A3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYP2A3 Protein

CYP2A3 Cat #

PR0101

CYP2A3 Source

recombinant

CYP2A3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYP2A3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYP2A3 Activity

N/A

Tag

CYP2A3 Contains A 6x histidine tag

CYP2A3 Formulation

Liquid

CYP2A3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYP2A3 family

Cytochrome P450 family

CYP2A3 Subcellular locations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

CYP2A3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.

CYP2A3 Sequence

DDBJ

EMBL

GenBank

CYP2A3 3D structure

ModBase

CYP2A3 interaction

STRING

CYP2A3 Proteomic

PRIDE

CYP2A3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYP2A3 Organism specific

CTD

MGI

CYP2A3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYP2A3 Gene expression

Bgee

ArrayExpress

Genevestigator

CYP2A3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY