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Human Cytochrome P450 2C8 (aa 1-490)

CYP2C8 Swiss Prot#

P10632

CYP2C8 Protein names

Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (P450 form 1) (P450 MP-12/MP-20) (P450 IIC2) (S-mephenytoin 4-hydroxylase)

CYP2C8 Gene names

CYP2C8

Organism

Human

CYP2C8 Entry name

CP2C8_HUMAN

CYP2C8 Codon optimized cDNA(gene) Clone

CYP2C8 Cat #

RPR0098

Tag

CYP2C8 contains A 6x histidine tag

CYP2C8 Formulation

Liquid

CYP2C8 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYP2C8 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYP2C8 Protein

CYP2C8 Cat #

PR0098

CYP2C8 Source

recombinant

CYP2C8 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYP2C8 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYP2C8 Activity

N/A

Tag

CYP2C8 Contains A 6x histidine tag

CYP2C8 Formulation

Liquid

CYP2C8 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYP2C8 family

Cytochrome P450 family

CYP2C8 Subcellular locations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

CYP2C8 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).

CYP2C8 Sequence

DDBJ

EMBL

GenBank

CYP2C8 3D structure

ModBase

CYP2C8 interaction

STRING

CYP2C8 Proteomic

PRIDE

CYP2C8 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYP2C8 Organism specific

CTD

MGI

CYP2C8 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYP2C8 Gene expression

Bgee

ArrayExpress

Genevestigator

CYP2C8 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY