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Human Platelet-activating factor acetylhydrolase (aa 22-441)

PAFAH Swiss Prot#

Q13093

PAFAH Protein names

Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (PAF 2-acylhydrolase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (2-acetyl-1-alkylglycerophosphocholine esterase) (1-alkyl-2-acetylglycerophosphocholine esterase)

PAFAH Gene names

PLA2G7 (PAFAH)

Organism

Human

PAFAH Entry name

PAFA_HUMAN

PAFAH Codon optimized cDNA(gene) Clone

PAFAH Cat #

RPR0084

Tag

PAFAH contains A 6x histidine tag

PAFAH Formulation

Liquid

PAFAH Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PAFAH Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PAFAH Protein

PAFAH Cat #

PR0084

PAFAH Source

recombinant

PAFAH Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PAFAH Purity

>90%, as determined by SDS-PAGE under reducing conditions

PAFAH Activity

N/A

Tag

PAFAH Contains A 6x histidine tag

PAFAH Formulation

Liquid

PAFAH Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PAFAH family

AB hydrolase superfamily, Lipase family

PAFAH Subcellular locations

Secreted > extracellular space.

PAFAH FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.

PAFAH Sequence

DDBJ

EMBL

GenBank

PAFAH 3D structure

ModBase

PAFAH interaction

STRING

PAFAH Proteomic

PRIDE

PAFAH Genome annotation

Ensembl

GeneID

KEGG

UCSC

PAFAH Organism specific

CTD

MGI

PAFAH Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PAFAH Gene expression

Bgee

ArrayExpress

Genevestigator

PAFAH Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY