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Human UV excision repair protein RAD23 homolog A (aa 1-363)

RAD23A Swiss Prot#

P54725

RAD23A Protein names

UV excision repair protein RAD23 homolog A (hHR23A)

RAD23A Gene names

RAD23A

Organism

Human

RAD23A Entry name

RD23A_HUMAN

RAD23A Codon optimized cDNA(gene) Clone

RAD23A Cat #

RPR0068

Tag

RAD23A contains A 6x histidine tag

RAD23A Formulation

Liquid

RAD23A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RAD23A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RAD23A Protein

RAD23A Cat #

PR0068

RAD23A Source

recombinant

RAD23A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RAD23A Purity

>90%, as determined by SDS-PAGE under reducing conditions

RAD23A Activity

N/A

Tag

RAD23A Contains A 6x histidine tag

RAD23A Formulation

Liquid

RAD23A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RAD23A family

RAD23 family

RAD23A Subcellular locations

Nucleus.

RAD23A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; FUNCTION: Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC.; FUNCTION: Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome.

RAD23A Sequence

DDBJ

EMBL

GenBank

RAD23A 3D structure

ModBase

RAD23A interaction

STRING

RAD23A Proteomic

PRIDE

RAD23A Genome annotation

Ensembl

GeneID

KEGG

UCSC

RAD23A Organism specific

CTD

MGI

RAD23A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RAD23A Gene expression

Bgee

ArrayExpress

Genevestigator

RAD23A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY