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Human DnaJ homolog subfamily B member 6 (aa 1-326)
HSJ2 Swiss Prot#
O75190
HSJ2 Protein names
DnaJ homolog subfamily B member 6 (Heat shock protein J2) (HSJ-2) (MSJ-1) (HHDJ1) (MRJ)
HSJ2 Gene names
DNAJB6 (HSJ2) (MRJ) (MSJ1)
Organism
Human
HSJ2 Entry name
DNJB6_HUMAN
HSJ2 Codon optimized cDNA(gene) Clone
HSJ2 Cat #
RPR0056
Tag
HSJ2 contains A 6x histidine tag
HSJ2 Formulation
Liquid
HSJ2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
HSJ2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant HSJ2 Protein
HSJ2 Cat #
PR0056
HSJ2 Source
recombinant
HSJ2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
HSJ2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
HSJ2 Activity
N/A
Tag
HSJ2 Contains A 6x histidine tag
HSJ2 Formulation
Liquid
HSJ2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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HSJ2 family
-
HSJ2 Subcellular locations
Cytoplasm > perinuclear region. Nucleus.
HSJ2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Reduces huntingtin aggregation associated with HD. Also reduces cellular toxicity and caspase-3 activity.
HSJ2 Sequence
DDBJ EMBL GenBank
HSJ2 3D structure
ModBase
HSJ2 interaction
STRING
HSJ2 Proteomic
PRIDE
HSJ2 Genome annotation
Ensembl GeneID KEGG UCSC
HSJ2 Organism specific
CTD MGI
HSJ2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
HSJ2 Gene expression
Bgee ArrayExpress Genevestigator
HSJ2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY