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| Human Deleted in malignant brain tumors 1 protein (aa 1-2413 ) |
| GP340 Swiss Prot# | | Q9UGM3 |
| GP340 Protein names | | Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) |
| GP340 Gene names | | DMBT1 GP340 |
| Organism | | Homo sapiens (Human) |
| GP340 Entry name | | DMBT1_HUMAN |
| GP340 Codon optimized cDNA(gene) Clone |
| GP340 Cat # | | RPY2737 |
| Tag | | GP340 contains A 6x histidine tag |
| GP340 Formulation | | Liquid |
| GP340 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| GP340 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant GP340 Protein |
| GP340 Cat # | | PY2737 |
| GP340 Source | | recombinant |
| GP340 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| GP340 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| GP340 Activity | | N/A |
| Tag | | GP340 Contains A 6x histidine tag |
| GP340 Formulation | | Liquid |
| GP340 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant GP340 Products | | For pricing and availability Click Here >>> |
| GP340 family | | DMBT1 family |
| GP340 Subcellular locations | | Secreted. |
| GP340 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell. |
| GP340 Sequence | | DDBJ | EMBL | GenBank |
| GP340 3D structure | | ModBase |
| GP340 interaction | | STRING |
| GP340 Proteomic | | PRIDE |
| GP340 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| GP340 Organism specific | | CTD | MGI |
| GP340 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| GP340 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| GP340 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
