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Human Kinetochore-associated protein 1 (aa 1-2209 )
KNTC1 Swiss Prot#
P50748
KNTC1 Protein names
Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)
KNTC1 Gene names
KNTC1 KIAA0166
Organism
Homo sapiens (Human)
KNTC1 Entry name
KNTC1_HUMAN
KNTC1 Codon optimized cDNA(gene) Clone
KNTC1 Cat #
RPY2715
Tag
KNTC1 contains A 6x histidine tag
KNTC1 Formulation
Liquid
KNTC1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
KNTC1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant KNTC1 Protein
KNTC1 Cat #
PY2715
KNTC1 Source
recombinant
KNTC1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
KNTC1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
KNTC1 Activity
N/A
Tag
KNTC1 Contains A 6x histidine tag
KNTC1 Formulation
Liquid
KNTC1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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KNTC1 family
-
KNTC1 Subcellular locations
Cytoplasm. Nucleus. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle.
KNTC1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.
KNTC1 Sequence
DDBJ EMBL GenBank
KNTC1 3D structure
ModBase
KNTC1 interaction
STRING
KNTC1 Proteomic
PRIDE
KNTC1 Genome annotation
Ensembl GeneID KEGG UCSC
KNTC1 Organism specific
CTD MGI
KNTC1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
KNTC1 Gene expression
Bgee ArrayExpress Genevestigator
KNTC1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY