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Human SH3 multiple ankyrin repeat domains protein 1 (aa 1-2161 )

SHANK1 Swiss Prot#

Q9Y566

SHANK1 Protein names

SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)

SHANK1 Gene names

SHANK1

Organism

Homo sapiens (Human)

SHANK1 Entry name

SHAN1_HUMAN

SHANK1 Codon optimized cDNA(gene) Clone

SHANK1 Cat #

RPY2709

Tag

SHANK1 contains A 6x histidine tag

SHANK1 Formulation

Liquid

SHANK1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SHANK1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SHANK1 Protein

SHANK1 Cat #

PY2709

SHANK1 Source

recombinant

SHANK1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SHANK1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SHANK1 Activity

N/A

Tag

SHANK1 Contains A 6x histidine tag

SHANK1 Formulation

Liquid

SHANK1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SHANK1 family

SHANK family

SHANK1 Subcellular locations

Cytoplasm. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse.

SHANK1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

SHANK1 Sequence

DDBJ

EMBL

GenBank

SHANK1 3D structure

ModBase

SHANK1 interaction

STRING

SHANK1 Proteomic

PRIDE

SHANK1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SHANK1 Organism specific

CTD

MGI

SHANK1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SHANK1 Gene expression

Bgee

ArrayExpress

Genevestigator

SHANK1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY