|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mouse Deleted in malignant brain tumors 1 protein (aa 1-2085 ) |
| Crpd Swiss Prot# | | Q60997 |
| Crpd Protein names | | Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80) |
| Crpd Gene names | | Dmbt1 Crpd |
| Organism | | Mus musculus (Mouse) |
| Crpd Entry name | | DMBT1_MOUSE |
| Crpd Codon optimized cDNA(gene) Clone |
| Crpd Cat # | | RPY2694 |
| Tag | | Crpd contains A 6x histidine tag |
| Crpd Formulation | | Liquid |
| Crpd Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Crpd Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Crpd Protein |
| Crpd Cat # | | PY2694 |
| Crpd Source | | recombinant |
| Crpd Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Crpd Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Crpd Activity | | N/A |
| Tag | | Crpd Contains A 6x histidine tag |
| Crpd Formulation | | Liquid |
| Crpd Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Crpd Products | | For pricing and availability Click Here >>> |
| Crpd family | | DMBT1 family |
| Crpd Subcellular locations | | Secreted. Cytoplasmic vesicle > secretory vesicle membrane; Single-pass membrane protein; Lumenal side. |
| Crpd FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract (By similarity). Required for terminal differentiation of columnar epithelial cells during early embryogenesis. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell. |
| Crpd Sequence | | DDBJ | EMBL | GenBank |
| Crpd 3D structure | | ModBase |
| Crpd interaction | | STRING |
| Crpd Proteomic | | PRIDE |
| Crpd Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Crpd Organism specific | | CTD | MGI |
| Crpd Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Crpd Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Crpd Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |