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Human Plexin-A1 (aa 1-1896 )

NOV Swiss Prot#

Q9UIW2

NOV Protein names

Plexin-A1 (Semaphorin receptor NOV)

NOV Gene names

PLXNA1 NOV PLXN1

Organism

Homo sapiens (Human)

NOV Entry name

PLXA1_HUMAN

NOV Codon optimized cDNA(gene) Clone

NOV Cat #

RPY2655

Tag

NOV contains A 6x histidine tag

NOV Formulation

Liquid

NOV Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NOV Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NOV Protein

NOV Cat #

PY2655

NOV Source

recombinant

NOV Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NOV Purity

>90%, as determined by SDS-PAGE under reducing conditions

NOV Activity

N/A

Tag

NOV Contains A 6x histidine tag

NOV Formulation

Liquid

NOV Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NOV family

Plexin family

NOV Subcellular locations

Membrane; Single-pass type I membrane protein.

NOV FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

NOV Sequence

DDBJ

EMBL

GenBank

NOV 3D structure

ModBase

NOV interaction

STRING

NOV Proteomic

PRIDE

NOV Genome annotation

Ensembl

GeneID

KEGG

UCSC

NOV Organism specific

CTD

MGI

NOV Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NOV Gene expression

Bgee

ArrayExpress

Genevestigator

NOV Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY