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Human CDK5 regulatory subunit-associated protein 2 (aa 1-1893 )

CEP215 Swiss Prot#

Q96SN8

CEP215 Protein names

CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)

CEP215 Gene names

CDK5RAP2 CEP215 KIAA1633

Organism

Homo sapiens (Human)

CEP215 Entry name

CK5P2_HUMAN

CEP215 Codon optimized cDNA(gene) Clone

CEP215 Cat #

RPY2651

Tag

CEP215 contains A 6x histidine tag

CEP215 Formulation

Liquid

CEP215 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CEP215 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CEP215 Protein

CEP215 Cat #

PY2651

CEP215 Source

recombinant

CEP215 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CEP215 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CEP215 Activity

N/A

Tag

CEP215 Contains A 6x histidine tag

CEP215 Formulation

Liquid

CEP215 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CEP215 family

-

CEP215 Subcellular locations

Cytoplasm > cytoskeleton > centrosome. Golgi apparatus. Cytoplasm.

CEP215 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends.

CEP215 Sequence

DDBJ

EMBL

GenBank

CEP215 3D structure

ModBase

CEP215 interaction

STRING

CEP215 Proteomic

PRIDE

CEP215 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CEP215 Organism specific

CTD

MGI

CEP215 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CEP215 Gene expression

Bgee

ArrayExpress

Genevestigator

CEP215 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY