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Human Dedicator cytokinesis protein 2 (aa 1-1830 )

DOCK2 Swiss Prot#

Q92608

DOCK2 Protein names

Dedicator of cytokinesis protein 2

DOCK2 Gene names

DOCK2 KIAA0209

Organism

Homo sapiens (Human)

DOCK2 Entry name

DOCK2_HUMAN

DOCK2 Codon optimized cDNA(gene) Clone

DOCK2 Cat #

RPY2636

Tag

DOCK2 contains A 6x histidine tag

DOCK2 Formulation

Liquid

DOCK2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DOCK2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DOCK2 Protein

DOCK2 Cat #

PY2636

DOCK2 Source

recombinant

DOCK2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DOCK2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DOCK2 Activity

N/A

Tag

DOCK2 Contains A 6x histidine tag

DOCK2 Formulation

Liquid

DOCK2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DOCK2 family

DOCK family

DOCK2 Subcellular locations

Endomembrane system; Peripheral membrane protein. Cytoplasm > cytoskeleton.

DOCK2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2 small GTPases, probably by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

DOCK2 Sequence

DDBJ

EMBL

GenBank

DOCK2 3D structure

ModBase

DOCK2 interaction

STRING

DOCK2 Proteomic

PRIDE

DOCK2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DOCK2 Organism specific

CTD

MGI

DOCK2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DOCK2 Gene expression

Bgee

ArrayExpress

Genevestigator

DOCK2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY