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Rat Signal-induced proliferation-associated 1-like 1 (aa 1-1822 )

Spa1 Swiss Prot#

O35412

Spa1 Protein names

Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (SPA-1-like protein p1294) (Spine-associated Rap GTPase-activating protein) (SPAR)

Spa1 Gene names

Sipa1l1 Spa1

Organism

Rattus norvegicus (Rat)

Spa1 Entry name

SI1L1_RAT

Spa1 Codon optimized cDNA(gene) Clone

Spa1 Cat #

RPY2628

Tag

Spa1 contains A 6x histidine tag

Spa1 Formulation

Liquid

Spa1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Spa1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Spa1 Protein

Spa1 Cat #

PY2628

Spa1 Source

recombinant

Spa1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Spa1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Spa1 Activity

N/A

Tag

Spa1 Contains A 6x histidine tag

Spa1 Formulation

Liquid

Spa1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Spa1 family

-

Spa1 Subcellular locations

Cytoplasm > cytoskeleton. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome.

Spa1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis.

Spa1 Sequence

DDBJ

EMBL

GenBank

Spa1 3D structure

ModBase

Spa1 interaction

STRING

Spa1 Proteomic

PRIDE

Spa1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Spa1 Organism specific

CTD

MGI

Spa1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Spa1 Gene expression

Bgee

ArrayExpress

Genevestigator

Spa1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY