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Human Adenylate cyclase type 10 (aa 1-1610 )

SAC Swiss Prot#

Q96PN6

SAC Protein names

Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase)

SAC Gene names

ADCY10 SAC

Organism

Homo sapiens (Human)

SAC Entry name

ADCYA_HUMAN

SAC Codon optimized cDNA(gene) Clone

SAC Cat #

RPY2571

Tag

SAC contains A 6x histidine tag

SAC Formulation

Liquid

SAC Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SAC Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SAC Protein

SAC Cat #

PY2571

SAC Source

recombinant

SAC Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SAC Purity

>90%, as determined by SDS-PAGE under reducing conditions

SAC Activity

N/A

Tag

SAC Contains A 6x histidine tag

SAC Formulation

Liquid

SAC Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SAC family

Adenylyl cyclase class-4/guanylyl cyclase family

SAC Subcellular locations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm > cytoskeleton. Cytoplasm > perinuclear region.

SAC FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation.

SAC Sequence

DDBJ

EMBL

GenBank

SAC 3D structure

ModBase

SAC interaction

STRING

SAC Proteomic

PRIDE

SAC Genome annotation

Ensembl

GeneID

KEGG

UCSC

SAC Organism specific

CTD

MGI

SAC Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SAC Gene expression

Bgee

ArrayExpress

Genevestigator

SAC Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY